Tag: services and resources

“What drives me is that we share a common goal: to provide the most accurate and up-to-date open knowledge to support research.” Meet Elisabeth Coudert, at SIB since 2000, who is leading the Annotation Enhancements team in the Swiss-Prot Group....

Discover the 10 best achievements and work produced by our scientists over the last year.

“The flexibility offered by SIB is quite unique”: find out more on the themes of learning and development at the institute and meet Monique Zahn, at SIB since 2012 and who recently took on a new role as Biodata Resources Support Manager, in...

Discover a method to automatically generates queries and democratize glycoinformatics.

The ‘MHC motif atlas’ interprets data to understand binding specificities. in silico talks – The latest in bioinformatics, by SIB Scientists

A major step ensuring sustainability of Swiss-made biodata resources.

SIB experts and resources are taking part in the global effort to develop dedicated data services, analysis tools and improve knowledge sharing to fight the COVID-19 pandemic.

Discover a library of interactive cell images for the visualization of subcellular location data.

Interview in Basler Zeitung – Life science special supplement (02.09.22), by Alexandra Bucher (edited for length and translated from German).

To understand and fight melanoma, it is essential to identify the genes involved in it. What if such information could be automatically retrieved and annotated from the vast research literature? In this in silico talk, SIB Group Leader Fabio...

To provide the global bioinformatics community with a shortlist of achievements of the year by SIB Scientists that are particularly deserving attention, here are the SIB Remarkable Outputs of 2021.

If you are working in computer-aided drug design, this in silico talk is for you: SIB Senior Research Scientist Ute Röhrig takes you on a journey to push the boundaries of knowledge around IDO1 and its role in immunotherapy resistance.

This is the summary description of this new research infrastructure, submitted to the SERI Research Infrastructure Roadmap 2023. Switzerland is at the forefront of the data revolution in the life sciences. To support this transformation, Swiss...

Animals as different as wasps and snakes have adopted surprisingly similar molecular mechanisms to squirt toxins out of their specialized cells. This is revealed by a study led by SIB scientists, who have conducted the first comparative analysis of...

After setting up the Swiss SARS-CoV-2 data hub, SIB is now co-leading an international project to facilitate open sharing of viral genomic sequences in other countries. Through SIB, Switzerland will thus be sharing its experience setting up and...

Today, the delta variant of the virus dominates the Swiss landscape. This is only possible thanks to an unprecedented sequencing effort. At the heart of the process, a national infrastructure, co-led by the SIB Swiss Institute of Bioinformatics,...

Discover the SwissBioData ecosystem, a proposal by the SIB Swiss Institute of Bioinformatics and 13 Swiss institutions, which aims at enabling next-generation data-driven research to boost Switzerland’s capacity to convert biological and biomedical...

If you are a researcher using single-cell transcriptomics to study immunology-related problems, you are probably on the lookout for a way to efficiently characterize cell states. This in silico talk presents a powerful tool (ProjecTILs) and...

If you are interested in making the most of your scientific website, database or software, learning how to convert user feedback into new developments is key. And putting the user at the centre was a key aspect of the redesign of Expasy, our...

Capturing biological pathways is a massive database challenge: it implies representing metabolites in a way that is understandable to both humans and computers, and which enables their interconnection through the biochemical reactions they engage...

Discover the SIB Remarkable Outputs 2020, a list of ‘must-read’ works by SIB Members produced in 2020 and selected by a committee of SIB Group Leaders and Researchers.

Over the past weeks and with the threat of emerging variants growing, pressing calls for an open sharing of SARS-CoV-2 sequencing data were issued by the scientific community. Such sharing would allow fast, representative and large-scale research...

A global group of researchers is calling for better integration of viral genetics, bioinformatics, and public health to enable better pandemic response now and better pandemic preparedness in the future.

The SIB Resource Bgee is a database for retrieval and comparison of gene expression patterns across multiple animal species. It provides an intuitive answer to the question “where is a gene expressed?” and supports research in cancer and...

Two further resources developed by SIB Groups have been designated as of crucial importance for life sciences, as a result of the latest edition of the selection process led by ELIXIR at the European level: Cellosaurus and Rhea.

The Human Proteome Project (HPP) of the Human Proteome Organisation (HUPO) is ten years old. Its mission? To generate the map of the protein-based molecular architecture of the human body.

Exploring the 160 databases and software tools developed by SIB Groups has never been this easy. Created in 1993, Expasy, the SIB bioinformatics resource portal, is now available as a new release, after a major overhaul.

In this in silico talk, SIB’s Ugnė Stolz from Tanja Stadler’s Group at ETH Zurich introduces CoalRe, a framework enabling to take into account reassortment when inferring virus evolution and infection pathways.

A changing planet threatens many species, including bumblebees - globally important pollinators in natural ecosystems and in agricultural food production. An international team co-led by SIB researchers at the University of Lausanne sequenced the...

The SIB CALIPHO Group and ENYO Pharma SA worked hand-in-hand in a transnational public-private partnership (PPP) to make human protein interaction data publicly available and FAIR, through the SIB Resource neXtProt.

In its latest version, the cancer diagnostics platform developed jointly by the Geneva University Hospitals (HUG) and SIB offers key additional molecular insights.

A benchmarking study of models predicting the location and sequence of transcription factor binding sites has been undertaken by an international team led by researchers at SIB, EPFL and the Russian Academy of Sciences.

Discover the SIB Remarkable Outputs 2019, a list of ‘must-read’ works by SIB Members produced in 2019 and selected by a committee of SIB Group Leaders and Researchers.

The Global Biodata Coalition (GBC), an international coalition of research funders to better coordinate approaches for the efficient funding, management and growth of biodata resources worldwide has been created. Its set-up is co-piloted by SIB.

Welcome to the latest activity report of the SIB Swiss Institute of Bioinformatics. To get a sense of its diverse nationwide community of Data scientists for life, across 80 Groups and top institutions in Switzerland, simply start browsing!

Scientists at SIB and the University of Basel, and Chelonia Applied Sciences (Basel), are part of a European effort to find molecules active against COVID-19 - and to accelerate this process in the future.

From where did the new coronavirus (nCoV, see box) arise, and how did it move to humans? How is it spreading and evolving? How can we develop therapies to treat it? SIB Groups provide a range of tools and resources that can help researchers answer...

An international team of scientists report in the journal Genome Biology results from a pilot project, co-led by SIB Group Leader Robert Waterhouse at the University of Lausanne, to kick-start the global sequencing initiative of thousands of...

SIB Scientists demonstrate how genome-comparison-based evolutionary approaches can be used to improve draft assemblies.

Uncover known – as well as yet uncharacterized - Toxin-Antitoxin Systems in your bacterial genomes, with this discovery pipeline and database

A new tool and web-platform bringing together leading orthology SIB resources to take the pain out of your evolutionary inference or functional annotation analyses

Discover, in a short video clip, SIB’s vision on Open Data, one of the many facets of Open Science – the movement to make scientific research and its dissemination accessible to all levels of the society.

A behind-the-scenes look at a recent paper on the origin of beetle biodiversity, and the bioinformatics tools used along the way.

The three laureates of this 10th edition of the SIB Bioinformatics Awards were announced during the [BC]2 Basel Computational Biology Conference held in Basel from 9 to 11 September.

SIB Group Leader Frédérique Lisacek, glycoinformatician, and Philippe Le Mercier, molecular virologist, present a dynamic view of their recent joint paper on this topic and provide a tour d’horizon of the tools developed at SIB that can be used to...

SIB Group Leader Niko Beerenwinkel at ETH Zurich introduces V-Pipe, a new end-to-end pipeline tool to mine viral genomes and improve clinical diagnostics.

How does this insect, which is an important model species, feed on poisonous milkweed seeds and use the acquired toxins for its own protection and bright red warning colouration? To explore these phenomena, an international study including SIB...

Are you a bioinformatician with a remarkable early career, a graduate student who published an outstanding paper or did you develop a bioinformatics resource with an important impact on the life science community? SIB is supporting bioinformatics...

A new method to analyze genetic data, developed by two SIB Groups, shows that the relationships between living species, from bacteria to plants and animals, are different from previous estimates. Created by the group led by Nicolas Salamin and the...

Each year with the Overton Prize, the International Society for Computational Biology (ISCB) recognizes the outstanding achievements of an early to mid-career scientist who has made a significant contribution to the field of computational biology....