Tag: services and resources

  • “What drives me is that we share a common goal”- an interview with Elisabeth Coudert, Team Lead Biocuration

    “What drives me is that we share a common goal: to provide the most accurate and up-to-date open knowledge to support research.” Meet Elisabeth Coudert, at SIB since 2000, who is leading the Annotation Enhancements team in the Swiss-Prot Group....

  • Discover the SIB Remarkable Outputs 2022

    Discover the 10 best achievements and work produced by our scientists over the last year.

  • “The flexibility offered by SIB is quite unique”- an interview with Monique Zahn, Biodata Resources Support Manager

    “The flexibility offered by SIB is quite unique”: find out more on the themes of learning and development at the institute and meet Monique Zahn, at SIB since 2012 and who recently took on a new role as Biodata Resources Support Manager, in...

  • A tool to widen access to resources of glycobiology

    Discover a method to automatically generates queries and democratize glycoinformatics.

  • A database using machine learning to decipher peptides for T cell recognition

    The ‘MHC motif atlas’ interprets data to understand binding specificities. in silico talks – The latest in bioinformatics, by SIB Scientists

  • Three SIB knowledge bases recognized as critical for life science worldwide

    A major step ensuring sustainability of Swiss-made biodata resources.

  • SIB resources supporting SARS-CoV-2 research

    SIB experts and resources are taking part in the global effort to develop dedicated data services, analysis tools and improve knowledge sharing to fight the COVID-19 pandemic.

  • Adding cell images from SwissBiopics to your resource: why and how

    Discover a library of interactive cell images for the visualization of subcellular location data.

  • "It is urgent that we talk about antibiotic resistance"

    Interview in Basler Zeitung – Life science special supplement (02.09.22), by Alexandra Bucher (edited for length and translated from German).

  • AI-powered extraction of biomedical relationships from the literature

    To understand and fight melanoma, it is essential to identify the genes involved in it. What if such information could be automatically retrieved and annotated from the vast research literature? In this in silico talk, SIB Group Leader Fabio...

  • Discover the SIB Remarkable Outputs 2021

    To provide the global bioinformatics community with a shortlist of achievements of the year by SIB Scientists that are particularly deserving attention, here are the SIB Remarkable Outputs of 2021.

  • The quest for small-molecule cancer immunotherapeutics

    If you are working in computer-aided drug design, this in silico talk is for you: SIB Senior Research Scientist Ute Röhrig takes you on a journey to push the boundaries of knowledge around IDO1 and its role in immunotherapy resistance.

  • SwissBioData ecosystem: boosting Switzerland's data-intensive research in life sciences

    This is the summary description of this new research infrastructure, submitted to the SERI Research Infrastructure Roadmap 2023. Switzerland is at the forefront of the data revolution in the life sciences. To support this transformation, Swiss...

  • Venom factories: a surprising molecular convergence, from wasps to snakes

    Animals as different as wasps and snakes have adopted surprisingly similar molecular mechanisms to squirt toxins out of their specialized cells. This is revealed by a study led by SIB scientists, who have conducted the first comparative analysis of...

  • SIB is co-steering European efforts to foster open sharing of SARS-CoV-2 genomic data

    After setting up the Swiss SARS-CoV-2 data hub, SIB is now co-leading an international project to facilitate open sharing of viral genomic sequences in other countries. Through SIB, Switzerland will thus be sharing its experience setting up and...

  • Switzerland establishes a national infrastructure to track COVID-19 and its variants

    Today, the delta variant of the virus dominates the Swiss landscape. This is only possible thanks to an unprecedented sequencing effort. At the heart of the process, a national infrastructure, co-led by the SIB Swiss Institute of Bioinformatics,...

  • SwissBioData: A proposal to boost data-driven discoveries in biology

    Discover the SwissBioData ecosystem, a proposal by the SIB Swiss Institute of Bioinformatics and 13 Swiss institutions, which aims at enabling next-generation data-driven research to boost Switzerland’s capacity to convert biological and biomedical...

  • Fast and automated interpretation of single-cell RNA-seq data

    If you are a researcher using single-cell transcriptomics to study immunology-related problems, you are probably on the lookout for a way to efficiently characterize cell states. This in silico talk presents a powerful tool (ProjecTILs) and...

  • Applying user-centred design in life science resources

    If you are interested in making the most of your scientific website, database or software, learning how to convert user feedback into new developments is key. And putting the user at the centre was a key aspect of the redesign of Expasy, our...

  • MetaNetX/MNXref: A unified namespace for metabolic models

    Capturing biological pathways is a massive database challenge: it implies representing metabolites in a way that is understandable to both humans and computers, and which enables their interconnection through the biochemical reactions they engage...

  • Discover the SIB Remarkable Outputs 2020

    Discover the SIB Remarkable Outputs 2020, a list of ‘must-read’ works by SIB Members produced in 2020 and selected by a committee of SIB Group Leaders and Researchers.

  • Accelerating global COVID-19 research with a Swiss SARS-CoV-2 Data Hub

    Over the past weeks and with the threat of emerging variants growing, pressing calls for an open sharing of SARS-CoV-2 sequencing data were issued by the scientific community. Such sharing would allow fast, representative and large-scale research...

  • How to track pandemic variants faster

    A global group of researchers is calling for better integration of viral genetics, bioinformatics, and public health to enable better pandemic response now and better pandemic preparedness in the future.

  • From v1 to v14: the gene expression database Bgee under the spotlight

    The SIB Resource Bgee is a database for retrieval and comparison of gene expression patterns across multiple animal species. It provides an intuitive answer to the question “where is a gene expressed?” and supports research in cancer and...

  • Cellosaurus and Rhea join the portfolio of ELIXIR Core Data Resources

    Two further resources developed by SIB Groups have been designated as of crucial importance for life sciences, as a result of the latest edition of the selection process led by ELIXIR at the European level: Cellosaurus and Rhea.

  • 10 years of Human Proteome Project with neXtProt as reference database

    The Human Proteome Project (HPP) of the Human Proteome Organisation (HUPO) is ten years old. Its mission? To generate the map of the protein-based molecular architecture of the human body.

  • Discover the new Expasy.org, the Swiss Bioinformatics Resource Portal

    Exploring the 160 databases and software tools developed by SIB Groups has never been this easy. Created in 1993, Expasy, the SIB bioinformatics resource portal, is now available as a new release, after a major overhaul.

  • An improved view of influenza evolution with CoalRe

    In this in silico talk, SIB’s Ugnė Stolz from Tanja Stadler’s Group at ETH Zurich introduces CoalRe, a framework enabling to take into account reassortment when inferring virus evolution and infection pathways.

  • Understanding pollinators: genomic characterisation of bumblebee biodiversity

    A changing planet threatens many species, including bumblebees - globally important pollinators in natural ecosystems and in agricultural food production. An international team co-led by SIB researchers at the University of Lausanne sequenced the...

  • ENYO Pharma SA and SIB make human protein interaction data publicly available

    The SIB CALIPHO Group and ENYO Pharma SA worked hand-in-hand in a transnational public-private partnership (PPP) to make human protein interaction data publicly available and FAIR, through the SIB Resource neXtProt.

  • New development in the cancer diagnostics platform used at the HUG

    In its latest version, the cancer diagnostics platform developed jointly by the Geneva University Hospitals (HUG) and SIB offers key additional molecular insights.

  • An open resource to find most accurate DNA binding motifs

    A benchmarking study of models predicting the location and sequence of transcription factor binding sites has been undertaken by an international team led by researchers at SIB, EPFL and the Russian Academy of Sciences.

  • SIB Remarkable Outputs 2019

    Discover the SIB Remarkable Outputs 2019, a list of ‘must-read’ works by SIB Members produced in 2019 and selected by a committee of SIB Group Leaders and Researchers.

  • Global Biodata Coalition: a champion for essential biological databases

    The Global Biodata Coalition (GBC), an international coalition of research funders to better coordinate approaches for the efficient funding, management and growth of biodata resources worldwide has been created. Its set-up is co-piloted by SIB.

  • Latest SIB Profile: explore a year of Swiss bioinformatics

    Welcome to the latest activity report of the SIB Swiss Institute of Bioinformatics. To get a sense of its diverse nationwide community of Data scientists for life, across 80 Groups and top institutions in Switzerland, simply start browsing!

  • Swiss players join European effort to fight COVID-19 and future pandemics

    Scientists at SIB and the University of Basel, and Chelonia Applied Sciences (Basel), are part of a European effort to find molecules active against COVID-19 - and to accelerate this process in the future.

  • SIB experts and resources in the fight against coronavirus

    From where did the new coronavirus (nCoV, see box) arise, and how did it move to humans? How is it spreading and evolving? How can we develop therapies to treat it? SIB Groups provide a range of tools and resources that can help researchers answer...

  • Unravelling arthropod genomic diversity over 500 million years of evolution

    An international team of scientists report in the journal Genome Biology results from a pilot project, co-led by SIB Group Leader Robert Waterhouse at the University of Lausanne, to kick-start the global sequencing initiative of thousands of...

  • Improved genome assemblies guided by evolution

    SIB Scientists demonstrate how genome-comparison-based evolutionary approaches can be used to improve draft assemblies.

  • TASmania – A new resource for microbiologists

    Uncover known – as well as yet uncharacterized - Toxin-Antitoxin Systems in your bacterial genomes, with this discovery pipeline and database

  • SwissOrthology – Your one-stop shop for orthologs

    A new tool and web-platform bringing together leading orthology SIB resources to take the pain out of your evolutionary inference or functional annotation analyses

  • From Open Data to Open Knowledge: a video!

    Discover, in a short video clip, SIB’s vision on Open Data, one of the many facets of Open Science – the movement to make scientific research and its dissemination accessible to all levels of the society.

  • An inordinate fondness for beetles, or an arms race with plants?

    A behind-the-scenes look at a recent paper on the origin of beetle biodiversity, and the bioinformatics tools used along the way.

  • SIB Bioinformatics Awards 2019: a series of talks to discover the laureates’ achievements

    The three laureates of this 10th edition of the SIB Bioinformatics Awards were announced during the [BC]2 Basel Computational Biology Conference held in Basel from 9 to 11 September.

  • Mind the sugars – Of the importance of glycans in vaccine design and viral infection

    SIB Group Leader Frédérique Lisacek, glycoinformatician, and Philippe Le Mercier, molecular virologist, present a dynamic view of their recent joint paper on this topic and provide a tour d’horizon of the tools developed at SIB that can be used to...

  • V-Pipe: an SIB Resource to mine viral genomes and improve clinical diagnostics

    SIB Group Leader Niko Beerenwinkel at ETH Zurich introduces V-Pipe, a new end-to-end pipeline tool to mine viral genomes and improve clinical diagnostics.

  • A major boost for insect biodiversity studies with the sequencing of the milkweed bug genome

    How does this insect, which is an important model species, feed on poisonous milkweed seeds and use the acquired toxins for its own protection and bright red warning colouration? To explore these phenomena, an international study including SIB...

  • The call for the SIB Bioinformatics Awards 2019 is closing soon - apply now!

    Are you a bioinformatician with a remarkable early career, a graduate student who published an outstanding paper or did you develop a bioinformatics resource with an important impact on the life science community? SIB is supporting bioinformatics...

  • Software promises to redefine the tree of life as we know it

    A new method to analyze genetic data, developed by two SIB Groups, shows that the relationships between living species, from bacteria to plants and animals, are different from previous estimates. Created by the group led by Nicolas Salamin and the...

  • Christophe Dessimoz is awarded the 2019 ISCB Overton Prize

    Each year with the Overton Prize, the International Society for Computational Biology (ISCB) recognizes the outstanding achievements of an early to mid-career scientist who has made a significant contribution to the field of computational biology....