prolfqua: A comprehensive R package for protein differential expression analysis

Mass spectrometry is an essential tool for quantifying the presence of various peptides and proteins in biological samples. To streamline this analysis, the Proteome Informatics FGCZ group led by Christian Panse has developed the R package prolfqua. In this in silico talk, Witold Wolski introduces the package's design and how to use it to analyze the differential expression of peptides or proteins. If you are interested in protein quantification using mass spectrometry and differential expression analysis, this talk is for you!

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Speaker

Name:

Witold E. Wolski

Institute:

ETHZ & University of Zurich

Group:

Proteome Informatics FGCZ

Witold E. Wolski obtained his doctorate in computational chemistry from the Free University Berlin, Germany, under the supervision of Knut Reinert, after which he undertook postdoctoral research at the School of Mathematics and Statistics at the University of Newcastle, UK. He worked for five years as a software engineer at Bruker Daltonics in Bremen, Germany, where he developed software for mass spectrometry. Then, he moved to Switzerland to provide bioinformatics support in the laboratory of Ruedi Aebersold. Witold has contributed to computational mass spectrometry and proteomics for over two decades and now works at the SIB Group led by Christian Panse at the Functional Genomics Center Zurich. His research interests include mathematical and statistical modeling of mass spectrometric proteomics and metabolomics data and data analysis automation.