A tool to widen access to resources of glycobiology

Many proteins on the surfaces of cells can have glycans present on them which allows their binding to other proteins. Studying the structures in these interactions could reveal valuable insights into physiological functions. Various databases have been developed for this purpose, but they often require knowledge of the SPARQL query language. In this in silico talk, Catherine Hayes from the group of Frédérique Lisacek presents GlycoQL, a tool that enables non-SPARQL experts to search for glycan structures, by generating automated queries. If you are an experimental or structural glycobiologist, or a computer scientist interested in democratizing your SPARQL queries, then this talk is for you!

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Speaker

Name:

Catherine Hayes

Institute:

University of Geneva

Group:

Proteome Informatics

Catherine Hayes received her PhD from the Chemistry Department of the National University of Ireland, Galway (NUIG) in 2009, on structural bioinformatics of protein-ligand interactions. Concurrently, she worked with the Centre for BioAnalytical Sciences (CBAS) on a glycan mass spectrometry project, before moving to the Biomedicine Department, University of Gothenburg to work with Niclas Karlsson on the structural elucidation of mucin type O-linked oligosaccharides. While in Gothenburg she also had project exchanges with the groups of Pauline Rudd (NIBRT, Dublin), Nicki Packer (Macquarie University, Sydney) and Frederique Lisacek (SIB, Geneva). After a break of some years she returned to the field, as a biocurator of GlyConnect (2020), again in the group of F. Lisacek. She is currently involved in biocuration, annotation, semantic web technologies and development of tools in both the glycomic and proteomic field.