Applying V-pipe to SARS-Coronavirus-2 data - now on YouTube

A recording of the webinar is available on YouTube.

Virus populations exist as heterogeneous ensembles of genomes within their hosts. This genetic diversity is associated with viral pathogenesis, virulence, and disease progression, and can be probed using high-throughput sequencing technologies.

This webinar explains — and demonstrates — the use of V-pipe, an end-to-end bioinformatics pipeline that integrates various computational tools for the analysis of SARS-Coronavirus-2 high-throughput sequencing data. It supports the reproducible analysis of genomic diversity in intra-host virus populations for both basic research and medical diagnostics.

V-pipe is developed by the Computational Biology Group of SIB Swiss Institute of Bioinformatics. This webinar is given by Ivan Topolsky, bioinformatician and medical doctor.

Structure

This webinar describes how to use V-pipe to analyze SARS-Coronavirus-2 high-throughput sequencing data.

This will be followed by a Question and Answer (Q&A) session.

Audience

PhD students, postdocs and other researchers, from any scientific environment (academia, facilities, companies, etc.) interested in SARS-CoV-2 data.

This webinar should be of interest to any researcher who aims to use viral next-generation sequencing (NGS) data, including experimental and computational researchers. It will be of particular interest to biologists and bioinformatics researchers who analyze viral NGS data in their work.

Learning objectives

At the end of this webinar, the participants will be able to:

• Access the V-pipe version adapted to SARS-CoV-2 data.
• Appreciate viral genomic diversity within coronavirus patients.
• Use the pipeline described.
• Understand publicly available tools.

Prerequisites

Knowledge / competencies

Experience in NGS data analysis is desirable.

Participants may wish to view the:

• YouTube video Mining viral genomes to improve clinical diagnostics
• V-pipe > SARS-CoV-2 web page

Technical

This webinar will be streamed via Zoom, you are thus required to have your own computer with an internet connection, Zoom installed and Firefox, Chrome, or Safari web browser installed.

Venue and Time

This webinar will be streamed to registered participants, and more information will be sent in due time.

The webinar will start at 14:00 CET and end around 15:00 CET.

Application

Attendance is free-of-charge, however registration is mandatory.

You will be informed by email of your registration confirmation.

Additional information

Coordination: Monique Zahn

You are welcome to register to the SIB courses mailing list to be informed of all future courses and workshops, as well as all important deadlines using the form here.

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For more information, please contact training@sib.swiss.