What we do
The individual cells of a body exhibit a stunning diversity of phenotypes, despite carrying a largely identical genetic makeup. This is due to the distinct ways in which the same genetic information can be read, interpreted and translated into function. At the RNA Regulatory Networks (RRN) Group at the Biozentrum in Basel, we combine computational modelling with big data and experimental analysis to discover and understand the regulatory networks governing the interpretation of genetic information at the level of tissues and single cells.
Find out more about the Group’s activities
Main publications 2020
- Ho-Xuan H et al.
Gene Expression Signatures of a Preclinical Mouse Model during Colorectal Cancer Progression under Low-Dose Metronomic Chemotherapy
Cancers, 10.3390/cancers13010049 - Jutzi D et al.
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis
Nature Communications, 10.1038/s41467-020-20191-3 - Ham D J et al.
The neuromuscular junction is a focal point of mTORC1 signaling in sarcopenia
Nature Communications, 10.1038/s41467-020-18140-1
