What we do

In the Bioinformatics Unravelling Group of the University of Fribourg (BUGFri), we support life science researchers by providing expertise in data analysis of next-generation sequencing experiments, or any large-scale biological experiment requiring bioinformatics resources. We focus on genome assembly, annotation and comparison, as well as on mutant and structure variant identification by resequencing. We also perform metagenomics, RNAseq and ChIPseq data analysis, proteome clustering and ortholog/paralog classification, as well as pathway and gene set enrichment analysis.

Find out more about the Group’s activities

Core facility activities

Here are some of the key services we provide (also see here):

  • Project planning and grant writing;
  • Software testing and development;
  • Data management plan (DMP) and deposition in OpenData repositories;
  • Data analysis;
  • Training.

Main publications 2021

  • Bouchemousse S et al.
    Genome Assembly of the Ragweed Leaf Beetle: A Step Forward to Better Predict Rapid Evolution of a Weed Biocontrol Agent to Environmental Novelties
    Genome Biol Evol, 10.1093/gbe/evaa102
  • Moreno-Indias I et al.
    Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions
    Front Microbiol, 10.3389/fmicb.2021.635781
  • Hill V et al.
    Minimalistic mycoplasmas harbor different functional toxin-antitoxin systems
    PLoS Genet, 10.1371/journal.pgen.1009365


university fribourg

Laurent Falquet
Bioinformatics Unravelling Group (BUGFri)
University of Fribourg
Group Webpage

Domain(s) of activity:

  • Genes and genomes
  • Comparative genomics
  • Data management
  • Data mining
  • Data visualisation
  • Deep sequencing data
  • Epigenetics
  • Genome reconstruction
  • Metagenomics
  • Microbiology
  • Training

Domain(s) of application:

  • Agriculture
  • Basic research
  • Medicine and health