What we do

The Computational Biology Group (CoBi) develops computational models of developmental processes. We focus on the delineation of fundamental developmental mechanisms and develop data-driven mechanistic 4D in silico models of organogenesis (mouse lung, kidney, pancreas, central nervous system, Drosophila wing and eye). The group runs a wet lab to obtain image data, and collaborates with clinicians to use its techniques to personalise medicine.

Find out more about the Group’s activities

Main publications 2021

  • Gomez H F et al.
    3D cell neighbour dynamics in growing pseudostratified epithelia
    elife, 10.7554/eLife.68135
  • Conrad L et al.
    The biomechanical basis of biased epithelial tube elongation in lung and kidney development
    Development, 10.1242/dev.194209
  • Boareto M et al.
    Positional information encoded in the dynamic differences between neighboring oscillators during vertebrate segmentation
    Cells & Development, 10.1016/j.cdev.2021.203737


University basel

Dagmar Iber
Computational Biology Group
ETH Zurich, D-BSSE, Basel
Group Webpage


Domain(s) of activity:

  • Systems biology
  • Systems biology
  • Biophysics
  • Cell mechanobiology
  • Deep sequencing data
  • Evo-Devo
  • Evolutionary biology
  • Experimental biology
  • Gene regulatory network analysis
  • In silico organogenesis
  • Mathematical modelling
  • Oncology
  • Personalised medicine
  • Signaling pathways
  • Single-cell biology
  • Software engineering
  • Transcriptomics

Domain(s) of application:

  • Medicine and health