At this special time of the year, we want to take the opportunity to thank you for your continued collaboration and support throughout 2020. Your commitment, ideas and projects keep us loving what we do each day.

2020 has been an intense and successful year for Swiss bioinformatics: we invite you to revisit some of its highlights in our last activity report, from which the image below is derived.

2021 promises to be yet another interesting year for SIB, from various training activities to new resources to be developed and discoveries to be made on the biomedical or biology front – and of course our [BC]2 Basel Computational Biology Conference, which will be held in Basel from 13 – 15 September 2021.

With all these plans ahead of us, we would like to extend our warmest holiday greetings to you and your family, and our best wishes for a New Year of good health.

Molecular modelling specialists at SIB, such as those in the Computer-aided molecular engineering group, develop tools to generate and interpret three-dimensional models of molecules. These models enable them to predict, for instance, the consequences of mutations detected in patients on drug resistance, thus supporting clinicians in tailoring treatments to individual patients.

On the image above, you can see a drug (here an immunosuppressant, Rapamycin, in purple), tightly bound to its target (here the protein complex between FKBP12 on the right and the mTOR on the left, in light blue).