Tag: personalised medicine

What we do Cardio-CARE is involved in the pre-processing, quality control and data analysis of high throughput Omics data. Other core competencies include the planning, conduct, and analysis of clinical studies, such as randomized controlled...

What we do The Genomics and Health Informatics (GHI) group aims to leverage the power of combined high-content sequencing, cellular imaging, and clinical data to address biological questions related to human disorders. Such questions include how...

From biomedical project planning to health data recruitment, from data transfer and analysis to their reuse: discover how the Swiss Personalized Health Network (SPHN) initiative, a project of the Swiss Academy of Medical Sciences and SIB, helps...

What we do The Translational Data Science (TDS) group focuses on developing novel computational tools, statistical methods and machine learning algorithms for the analysis of high-throughput and high-dimensional datasets generated by novel assay...

Could machine learning speed up the clinical identification of resistant microbes? Discover the database built by the team for that purpose, and the new method to retrieve even more information from MS data.

Have you ever wondered how bioinformatics contributes to health and biodiversity? What is the SIB Swiss Institute of Bioinformatics – in simple words?

Connecting researchers from across Switzerland with biomedical data to foster personalized health: this is the aim of the national secure computing network BioMedIT, set up by the SIB in collaboration with ETH Zurich and the University of Basel.

While most of the human genome is the same across individuals, genomic mishaps such as deletions and duplications can reduce or increase the number of copies of specific genetic fragments. These mishaps are also known as copy-number variations or...

For the first time, biomedical researchers can assess the availability of consented datasets over all five university hospitals in Switzerland at once.

The latest special issue of the journal Cell Genomics features a collection of perspective, opinion, Q&A and technical papers dedicated to the Global Alliance for Genomics and Health (GA4GH).

Swiss specialists in data semantics define the national strategy for the interoperability of research data to enable a strong policy of promoting personalised medicine.

Thanks to a unique dataset from living donors, and innovative multi-omics analysis, an international research team led by investigators at the Paul-Langerhans-Institute Dresden (PLID), the SIB Swiss Institute of Bioinformatics and the...

What we do Tumors are molecularly diverse and each tumor is an evolutionary system on its own. The inter- and intra-tumor heterogeneity influence the clinical and biological behavior of cancers and has important implications in tumor progression,...

What we do We are the Clinical Computational Biology group at the Institute for Chemistry and Bioanalytics, School for Life Sciences, FHNW. We offer bioinformatics support for various molecular diagnostic assays with a focus on comprehensive...

What we do The group Multi-omics for healthcare materials focuses on deconvolution of disease-associated cellular signaling networks in order to inform precise imunoengineering solutions. Activities of the group are centered on generating and...

What we do The Cancer Systems Immunology lab focuses on understanding how the immune system responds to cancer. We aim to define cancer-associated immune cell states, to identify the genetic programs that drive their differentiation, to reveal how...

The Swiss Variant Interpretation Platform for Oncology (SVIP-O) was launched by SIB, ETH Zurich and HES-SO to offer a harmonized interpretation of cancer variants to clinicians. SVIP-O, now available in its first public version,

A new version of ChromosomeWalk offers a gateway to an entertaining ‘genome browser’, enriched with a new selection of stories on fascinating genes – in English, French and German – as well to the PrecisionMed website for an illustrated tour of...

Find out about the current status of the Swiss Personalized Health Network (SPHN) – a project of the Swiss Academy of Medical Sciences (SAMS) and SIB -, its perspectives and goals for the next funding period.

As part of its infrastructure activities, SIB is in charge of BioMedIT, a secure and cutting-edge IT network across Switzerland, designed to support biomedical research and clinical bioinformatics.

Focus on the group's mission The Vital-IT team provides bioinformatics collaborative support to life science projects in Switzerland and abroad through collaborations with academic and industry partners. Thanks to its diverse expertise in...

Data management We organize, clean & control the quality of your datasets for subsequent analysis. In addition, we can process, transform and align your datasets to existing standards and make them available as a database. We can propose...

SIB, Lunaphore and the Geneva University Hospitals (HUG) are collaborating to enable precision cancer medicine. As part of an Innosuisse project, they aim to develop an integrative solution for the phenotypic analysis of tumors powered by automated...

SIB is joining the consortium ‘SOPHIA’ (Stratification of Obese Phenotypes to Optimize Future Obesity Therapy), which aims to improve risk assessment of complications of obesity and predict treatment response for people with obesity.

What we do The Snijder Lab is pioneering multiplexed image-based drug screening in patient biopsies, a technique we call pharmacoscopy, for both systems biology and personalized medicine. In an intervention trial, pharmacoscopy-guided treatments...

What we do The Computational Genetics and Epigenetics of Cancer Group aims to assess contribution of chromatin changes to cancer initiation and progression and associate them with genetic modifications. To achieve this goal, we employ advanced...

What we do The Clinical Proteotype Analysis Center in Zurich is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of disease/wellness, through the development and application of robust, quantitative,...

What we do The Clinical Proteotype Analysis Center in Zurich is a comprehensive and coordinated effort to accelerate the understanding of the molecular basis of disease/wellness, through the development and application of robust, quantitative,...

What we do Our group’s overall research focuses in the emerging field of artificial intelligence applied to health. Health data is generated from a variety of sources and comprises molecular profiles, medical records, digital biomarkers and social...

A short film to revisit the 14th [BC]2 Conference – one of the key bioinformatics events in Europe, which is organized by SIB – around the theme of Big Data in Molecular Medicine.

The PrecisionMed.ch website, developed by the SIB Swiss Institute of Bioinformatics, in collaboration with the University of Lausanne and the CHUV (Lausanne University Hospital), with the support of the SantéPerSo initiative, offers illustrated...

The three laureates of this 10th edition of the SIB Bioinformatics Awards were announced during the [BC]2 Basel Computational Biology Conference held in Basel from 9 to 11 September.

SIB Director Christine Durinx was interviewed by L’AGEFI, a Swiss daily newspaper focused on economics, finance and politics.

Health data from patients are typically generated and stored in a multitude of ways across Swiss hospitals. Making these data both accessible and useful to biomedical researchers is the goal of the Swiss Personalized Health Network initiative...

Being able to visualize the transmission of a virus in real-time during an outbreak, or to better adapt cancer treatment on the basis of the mutations present in a tumour’s individual cells are only two examples of what molecular Big Data can bring...

Join the international [BC]2 conference and EMBO meeting at BASEL LIFE from 9–12 September: a unique opportunity for today’s scientists to get insights and share the latest discoveries, resources and approaches to make sense of genomic and...

Thanks to the national initiative Swiss Personalized Health Network (SPHN), Switzerland is currently shifting from a fragmented health data landscape to a coordinated infrastructure enabling personalized health research. But how does this translate...

Personalized healthcare requires a solid foundation; establishing interoperability of biomedical information and building a national infrastructure provides such a basis. It is with this conviction that Katrin Crameri took over the reins of SIB’s...

In 2019, the SIB Bioinformatics Awards will be presented for the 10th time, providing a great occasion to reach out to past laureates and ask them where they are now in their career. In this interview, we met with Hannes Röst, recipient of the...

Today, we present an overview of the BioMedIT project, coordinated by SIB’s Personalized Health Informatics Group, as the first of a series of articles on SIB’s role in the development of a personalized health research infrastructure in...

The Global Alliance for Genomics and Health (GA4GH) has selected SPHN among its “2019 Driver Projects” that aim to develop and pilot standards for sharing genomic and health-related data.

The CINECA project, led by EMBL-EBI, aims to unite more than a million human data sets from across Africa, Canada and Europe. SIB is among the initiative’s 18 partner organisations...

On 16 December 2018, the count of total jobs run on the SIB Resource SwissDrugDesign passed the symbolic one-million mark.

Fifteen years after its creation, Vital-IT – one of SIB’s largest groups and Switzerland’s earliest bioinformatics core facility – continues to evolve. Find out how the Group is consolidating its position as the reference in bioinformatics for...

Bioinformatics is fundamental to precision medicine. But why? How do hospitals and researchers benefit from bioinformatics to help patients? Canal9 TV Channel, the Oncology department of UNIL/CHUV and SIB all set out together to find answers to...

The start of a new academic year is always a good time to engage in strategic thinking. What are the major themes for SIB's development? Where will SIB be adding value in the years to come? Following the directions set out in SIB's Roadmap, over...

Hundreds of SIB Members from across Switzerland came to Biel/Bienne on 26 June to attend the SIB Days – our 2-day internal conference and a unique opportunity for the bioinformatics community to connect.

What we do The laboratory specializes in the development of computer-aided algorithms, programs and databases for protein engineering, drug design and structure-based immunoinformatics with applications in oncology, notably in immunotherapy of...

What we do We are the NEXUS Personalized Health Technologies at the ETH Zurich. Our unit offers highly customizable bioinformatics, biostatistics and software engineering services for projects in the field of biomedical research and development....

What we do The Molecular Modelling Group studies molecular interactions using modelling techniques such as homology modelling, molecular dynamics, docking and free energy simulations. Our main activity consists in developing and applying methods...