Tag: next generation sequencing

What we do Cardio-CARE is involved in the pre-processing, quality control and data analysis of high throughput Omics data. Other core competencies include the planning, conduct, and analysis of clinical studies, such as randomized controlled...

Interview in Basler Zeitung – Life science special supplement (02.09.22), by Alexandra Bucher (edited for length and translated from German).

What we do The Translational Data Science (TDS) group focuses on developing novel computational tools, statistical methods and machine learning algorithms for the analysis of high-throughput and high-dimensional datasets generated by novel assay...

After setting up the Swiss SARS-CoV-2 data hub, SIB is now co-leading an international project to facilitate open sharing of viral genomic sequences in other countries. Through SIB, Switzerland will thus be sharing its experience setting up and...

Today, the delta variant of the virus dominates the Swiss landscape. This is only possible thanks to an unprecedented sequencing effort. At the heart of the process, a national infrastructure, co-led by the SIB Swiss Institute of Bioinformatics,...

What we do Tumors are molecularly diverse and each tumor is an evolutionary system on its own. The inter- and intra-tumor heterogeneity influence the clinical and biological behavior of cancers and has important implications in tumor progression,...

What we do We are the Clinical Computational Biology group at the Institute for Chemistry and Bioanalytics, School for Life Sciences, FHNW. We offer bioinformatics support for various molecular diagnostic assays with a focus on comprehensive...

Over the past weeks and with the threat of emerging variants growing, pressing calls for an open sharing of SARS-CoV-2 sequencing data were issued by the scientific community. Such sharing would allow fast, representative and large-scale research...

From SARS-CoV-2 monitoring to HIV antiviral drug resistance detection, the SIB Resource V-pipe orchestrates several software packages to detect the genomic diversity of a virus population in a sample or individual. 

In its latest version, the cancer diagnostics platform developed jointly by the Geneva University Hospitals (HUG) and SIB offers key additional molecular insights.

Focus on the group's mission The Vital-IT team provides bioinformatics collaborative support to life science projects in Switzerland and abroad through collaborations with academic and industry partners. Thanks to its diverse expertise in...

Data management We organize, clean & control the quality of your datasets for subsequent analysis. In addition, we can process, transform and align your datasets to existing standards and make them available as a database. We can propose...

What we do The Computational Genetics and Epigenetics of Cancer Group aims to assess contribution of chromatin changes to cancer initiation and progression and associate them with genetic modifications. To achieve this goal, we employ advanced...

What we do Our group’s overall research focuses in the emerging field of artificial intelligence applied to health. Health data is generated from a variety of sources and comprises molecular profiles, medical records, digital biomarkers and social...

Researchers from UNIL, UNIGE and SIB provide the researchers’ community with an extremely powerful computer tool to facilitate the interpretation of the genome’s Big Data

What we do Our group is interested in the regulatory machinery controlling gene expression. We investigate it by analyzing population scale multi-omics data sets (e.g. genomics, transcriptomics, epigenomics, proteomics) in which we use genetic...

Being able to visualize the transmission of a virus in real-time during an outbreak, or to better adapt cancer treatment on the basis of the mutations present in a tumour’s individual cells are only two examples of what molecular Big Data can bring...

Join the international [BC]2 conference and EMBO meeting at BASEL LIFE from 9–12 September: a unique opportunity for today’s scientists to get insights and share the latest discoveries, resources and approaches to make sense of genomic and...

What we do Sensory neural systems display stunning variation. Our aim is to investigate their evolution between species and populations. How do novel neural circuits emerge (and how are they lost)? What are the evolutionary forces that modify...

In 2019, the SIB Bioinformatics Awards will be presented for the 10th time, providing a great occasion to reach out to past laureates and ask them where they are now in their career. In this interview, we met with Inanc Birol, recipient of the...

In 2019, the SIB Bioinformatics Awards will be presented for the 10th time, providing a great occasion to reach out to past laureates and ask them where they are now in their career. In this interview, we met with Aitana Lebrand, recipient of the...

In 2019, the SIB Bioinformatics Awards will be presented for the 10th time, providing a great occasion to reach out to past laureates and ask them where they are now in their career. In this interview, we met with Lukas Burger, recipient of the...

In 2019, the SIB Bioinformatics Awards will be presented for the 10th time, providing a great occasion to reach out to past laureates and ask them where they are now in their career. In this interview, we met with Julien Roux, recipient of the 2009...

Bioinformatics is fundamental to precision medicine. But why? How do hospitals and researchers benefit from bioinformatics to help patients? Canal9 TV Channel, the Oncology department of UNIL/CHUV and SIB all set out together to find answers to...

Bacterial genomes are a treasure trove of information, be it for the development of novel antibiotics or the protection of crops against pathogens. A study, led by the group of SIB’s Christian Ahrens at Agroscope, shows that unravelling those...

What we do We are interested in studying ecological and evolutionary factors that determine the structure, function and diversity of microbial communities – with a focus on the ocean ecosystem and the gastrointestinal tract of animals and humans....

What we do We develop statistical and computational methods to answer biological questions from big data, from genomic sequence data to images. Our work is motivated by both the wealth of biological data currently being generated, as well as by...

What we do The group’s research is focused on elucidating interactions between gene evolution and gene function through developing computational approaches to interrogate evolutionary and functional genomics data. We are developing quantifications...

What we do We focus on the bioinformatic analysis and integration of state-of-the-art functional genomics data that we obtain through close collaboration with experimental biologists (genome sequences, gene and protein expression, metabolomics,...

What we do In the Statistical Bioinformatics Group, we develop robust data analysis solutions, including new or improved methods, for the analysis of genome-scale data. We develop statistical methods for interpreting data from high-throughput...

What we do In the Evolutionary Bioinformatics Group, we are interested in animal genome evolution with a focus on questions arising from evolutionary developmental biology (Evo-Devo). For this, we develop methods and databases to extract reliable...

What we do We study gene regulation through the analysis and modelling of genome-wide datasets. We collaborate closely with experimental researchers on various biological topics, including cancer progression, chromatin biology and cellular...

What we do In the Computational Evolution Group, we develop phylogenetic tools in order to understand evolutionary processes. Using our phylogenetic methods, we aim to improve our understanding of past evolutionary and population dynamic processes...

What we do In the Science IT (S3IT) unit, we provide support for science in general, and for life science and medicine in particular. S3IT serves as a partner for both local and national projects to enable competitive research with the advanced...

What we do We are dedicated to the processing, analysis and interpretation of next-generation sequencing data. We interact closely with research groups, and provide tailored comprehensive bioinformatics solutions. Additionally, we provide standard...

What we do We combine Evolutionary and Developmental Biology as well as genomic approaches with the study of physical processes to understand the mechanisms generating life’s complexity and diversity. The self-organizational capabilities of...

What we do Our group’s interest is focused on understanding how the interplay of population structure, trait architecture and selection can be disentangled. To this end, we use different approaches, from theory and the development of statistical...

What we do In the Laboratory of Systems Biology and Genetics (LSBG), we use high-throughput sequencing, single cell genomics, microfluidics, and computational approaches: to decipher the regulatory code in Drosophila and mammals with a specific...

What we do In the Interfaculty Bioinformatics Unit of the University of Bern (IBU), we provide services and expertise to assist researchers of the three “Life-Science” Faculties and Insel hospital in data analysis and project planning for...

What we do The Computational Biology Group is involved in research and teaching in the areas of computational biology, biostatistics, and systems biology. We aim at supporting the rational design of medical interventions in complex and rapidly...

The development of expertise in bioinformatics and genomics among future African scientists is key for finding solutions to local health problems. However such training and courses often rely on powerful and complex infrastructure.

With thousands of prokaryotic genomes newly sequenced each year, solutions for accurately annotating these genomes and thereby providing the basis for uncovering the function(s) of genes and their encoded proteins are urgently needed.

The University Hospital of Basel is launching a CAS in personalized molecular oncology with the SIB Swiss Institute of Bioinformatics and the University Hospital of Lausanne. First of its kind in Switzerland, this training takes place at a key...

On 28 September, the SIB Swiss Institute of Bioinformatics held its first course dedicated to clinicians and clinical laboratory professionals.This one-day course aimed at providing participants with a deepened knowledge, experience and...

“Stick out your tongue and say... ‘omics’”.In addition to patients’ vital signs or eating habits, molecular profiling data is increasingly becoming part of the medical practitioners’ toolbox. But these ‘omics’ data pose novel challenges, for...